Immune Responce in Mice Immunized with Live Cold-Adapted Influenza Vaccine in Combination with Chitosan-Based Adjuvants
Autor: | Akhmatova, Nelly К., Оlga V. Lebedinskaya, Ancha V. Baranova, Еlena А. Lebedinskaya, Sorokina, Ekaterina V., Akhmatov, Elvin А., Аnatoliy P. Godovalov, Markushin, Stanislav G. |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: | |
DOI: | 10.5281/zenodo.1076860 |
Popis: | An influence of intranasal combined injection of live cold-adapted influenza vaccine with chitosan derivatives as adjuvants on the subpopulation structure of mononuclear leukocytes of mouse spleen which reflects the orientation of the immune response was studied. It is found that the inclusion of chitosan preparations promotes activation of cellular-level of immune response. {"references":["N.K. Akhmatova, N.B. Egorova, E.A. Kurbatova, I.B. Semenova, O.M.\nKuz'menko, R.V. Shcherbakov, S.G. Markushin, Iu.Z. Gendon,\n\"Influence of chitosan on immunophenotype and functional activity of\nmurine mononuclear leukocytes after immunization with inactivated\ninfluenza vaccine\", Zh. Mikrobiol. Epidemiol. Immunobiol. Nov-\nDec;(6), 2008, pp. 31-35.","S.G. Markushin, Iu.Z. Gendon, G.G. Krivtsov, I.I. Akopova, A.S.\nSukhno, A.D. Pereverzev, \"Increase of immunogenicity of cold-adapted\ninfluenza vaccine by using adjuvant\", Zh. Mikrobiol. Epidemiol.\nImmunobiol. Sep-Oct ;(5), 2010, pp. 29-34.","A. Bacon, J. Makin, P.J. Sizer, I. Jabbal-Gill, M. Hinchcliffe, L. Illum, S.\nChatfield, M. Roberts, \"Carbohydrate biopolymers enhance antibody\nresponses to mucosally delivered vaccine antigens\", Infect. Immun., vol.\n68, 2000, pp. 5764-5770.","Y. Ghendon, S. Markushin, G. Krivtsov, I. Akopova, \"Chitosan as an\nadjuvant for parenterally administered inactivated influenza vaccines\",\nArch. Virol., vol. 153, 2008, pp. 831-837.","Y. Ghendon, S. Markushin, Y. Vasiliev, I. Akopova, I. Koptiaeva, G.\nKrivtsov, O. Borisova, N. Ahmatova, E. Kurbatova, S. Mazurina, V.\nGervazieva, \"Evaluation of properties of chitosan as an adjuvant for\ninactivated influenza vaccines administered parenterally\", Journal of\nMedical Virology, vol. 81, 2009, pp. 494-506.","R. Gupta, G. Siber, \"Adjuvant for human vaccines -current status,\nproblems and future prospects\", Vaccine, vol. 13, 1995, pp. 1263-1276.","L. Illum, \"Nasal drug delivery - possibilities, problems and solutions\", J.\nControl. Release, vol. 87, 2003, pp. 187-198.","L. Illum, I. Jabbal-Gill, M. Hinchcliffe, A.N. Fisher, S.S. Davis,\n\"Chitosan as a novel nasal delivery system for vaccines\", Adv. Drug.\nDeliv. Rev., vol. 51, 2001, pp. 81-96.","I.M. van der Lubben, J.C. Verhoef, G. Borchard, H.E. Junginger,\n\"Chitosan and its derivatives in mucosal drug and vaccine delivery\",\nEurop. J. Pharm. Sci., vol. 14, 2001, pp. 201-207.\n[10] I.M. van der Lubben, G. Kersten, M.M. Fretz, C. Beuvery, J. Coos\nVerhoef, H.E. Junginger, \"Chitosan microparticles for mucosal\nvaccination against diphtheria: oral and nasal efficacy studies in mice\",\nVaccine, vol. 21, 2003, pp. 1400-1408.\n[11] S.A. Kopecky-Bromberg, K.A. Fraser, N. Pica, E. Carnero, T.M. Moran,\nR.W. Franck, M. Tsuji, P. Palese, \"Alpha-C-galactosylceramide as an\nadjuvant for a live attenuated influenza virus vaccine\", Vaccine, vol.\n8;27(28), pp. 3766-3774.\n[12] A.R. Rekstin, K. Lu, D. Kats, L.G..Rudenko \"Production of early\ncytokines after infection with A/Leningrad/134/57 (H2N2) wide-type\nvirus and cold-adapted attenuated vaccine viruses\", Vopr. Virusol. Mar-\nApr; 51(2), 2006, pp. 27-30."]} |
Databáze: | OpenAIRE |
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