On the feasibility of improved target coverage without compromising organs at risk using online adaptive stereotactic partial breast irradiation (A‐SPBI)

Autor: Steven K, Montalvo, Nathan, Kim, Chika, Nwachukwu, Prasanna, Alluri, David, Parsons, Mu-Han, Lin, Bin, Cai, Tingliang, Zhuang, Brian, Hrycushko, Liyuan, Chen, Robert, Timmerman, Asal, Rahimi
Rok vydání: 2022
Předmět:
Zdroj: Journal of Applied Clinical Medical Physics. 24
ISSN: 1526-9914
DOI: 10.1002/acm2.13813
Popis: Describe an early-adopting institution's experience with online adaptive radiation for stereotactic partial breast irradiation.Retrospective review of 22 women treated between May 2021 and March 2022 with adaptive stereotactic partial breast irradiation. A total of 106 of 110 fractions were evaluated for dosimetric changes in target coverage and organ-at-risk (OAR) dose. Patient set up with stereotactic wooden frame and adapted per fraction. Treatment and planning times were collected prospectively by radiation therapists.Scheduled PTVAdaptive stereotactic breast irradiation resulted in improved target coverage with equivalent dosing to OARs in an efficient and tolerated treatment time. Improved target coverage allowed for decreased PTV margins compared to prior trial protocols that may improve acute and late toxicities.
Databáze: OpenAIRE