Selection and Functionalization of Germanium Nanowires for Bio-Sensing

Autor: Siriny Laumier, Thomas Farrow, Harm van Zalinge, Luca Seravalli, Matteo Bosi, Ian Sandall
Rok vydání: 2022
Předmět:
Zdroj: ACS omega. 7(39)
ISSN: 2470-1343
Popis: In this paper, we investigate the use of dielectrophoresis to align germanium nanowire arrays to realize nanowire-based diodes and their subsequent use for bio-sensing. After establishing that dielectrophoresis is a controllable and repeatable fabrication method to create devices from germanium nanowires, we use the optimum process conditions to form a series of diodes. These are subsequently functionalized with an aptamer, which is able to bind specifically to the spike protein of SARS-Cov2 and investigated as a potential sensor. We observe a linear increase in the source to drain current as the concentration of spike protein is increased from 100 fM/L to 1 nM/L.
Databáze: OpenAIRE