Microbiology of wound infection after oral cancer surgery
| Autor: | Silvana Udovic Gobic, David Harmicar, Margita Belušić-Gobić, Anamarija Predrijevac, Arijan Zubovic, Robert Cerović, Lorena Zubovic |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences
medicine.medical_specialty medicine.drug_class Wound infection Antibiotics Microbial Sensitivity Tests medicine.disease_cause Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Surgical Wound Infection Isolated microorganism Oral cancer Pathogen biology integumentary system business.industry Pseudomonas aeruginosa BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti Cancer 030206 dentistry Acinetobacter medicine.disease biology.organism_classification Cannula Enterobacteriaceae Anti-Bacterial Agents Otorhinolaryngology 030220 oncology & carcinogenesis Wound Infection Mouth Neoplasms Surgery Oral Surgery business Staphylococcus |
| Zdroj: | Journal of Cranio-Maxillofacial Surgery Volume 48 Issue 7 |
| ISSN: | 1010-5182 |
| Popis: | Introduction The aim of present study is to investigate the most common infection pathogen found in the postoperative wounds, following surgical treatment of oral and oropharyngeal cancer, in order to identify the most suitable antibiotic treatment. Patients and methods We analyzed patients with squamous cell cancer of oral and oropharyngeal region. In patients who developed postoperative wound infection, wound swabs were taken from three different sites: the cannula, wounds on the neck and wounds in the oral cavity. Results In total 195 patients were included. The postoperative wound infection was detected in 115 patients (59%). In average, the swabs were taken 8 days after the surgery. The similar bacterial species from all three sites were detected in 24 patients (12,3%). In comparison, we found that there was statistically significant difference in the bacteria abundance from all three sites (p=0,031). There were significantly more bacteria in the wounds of the neck than cannula (p=0,007) and in the wounds in the oral cavity than cannula (p=0,002). No statistically significant difference between the wound on the neck and in the oral cavity was found. The most frequently isolated bacterial family was Enterobacteriaceae. Other more commonly isolated bacteria species were Staphylococcus spp. (G+), Pseudomonas aeruginosa (G-), Corynebacteruim spp. (G +) and Acinetobacter baumanii (G-). Conclusion Based on the most commonly isolated groups of pathogens we concluded that probably the best empiric antibiotic treatment of wound infections until antibiogram is completed might be achieved from the group of aminoglycosides or quinolones. Antibiotic therapy should be reviewed if necessary when antibiogram is completed. |
| Databáze: | OpenAIRE |
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