Morinda citrifolia(Noni) as an Anti-Inflammatory Treatment in Women with Primary Dysmenorrhoea: A Randomised Double-Blind Placebo-Controlled Trial
| Autor: | Marvin Reid, Georgiana Gordon-Strachan, Horace Fletcher, J. C. Dawkins, Gillian Wharfe, Carole Rattray |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Randomization Article Subject Traditional medicine biology business.industry Anti inflammatory treatment Placebo-controlled study Obstetrics and Gynecology Primary dysmenorrhoea biology.organism_classification Placebo lcsh:Gynecology and obstetrics Double blind Morinda Internal medicine Clinical Study medicine business lcsh:RG1-991 After treatment |
| Zdroj: | Obstetrics and Gynecology International Obstetrics and Gynecology International, Vol 2013 (2013) |
| ISSN: | 1687-9597 1687-9589 |
| Popis: | Introduction. Noni (Morinda citrifolia) has been used for many years as an anti-inflammatory agent. We tested the efficacy of Noni in women with dysmenorrhea.Method. We did a prospective randomized double-blind placebo-controlled trial in 100 university students of 18 years and older over three menstrual cycles. Patients were invited to participate and randomly assigned to receive 400 mg Noni capsules or placebo. They were assessed for baseline demographic variables such as age, parity, and BMI. They were also assessed before and after treatment, for pain, menstrual blood loss, and laboratory variables: ESR, hemoglobin, and packed cell volume.Results. Of the 1027 women screened, 100 eligible women were randomized. Of the women completing the study, 42 women were randomized to Noni and 38 to placebo. There were no significant differences in any of the variables at randomization. There were also no significant differences in mean bleeding score or pain score at randomization. Both bleeding and pain scores gradually improved in both groups as the women were observed over three menstrual cycles; however, the improvement was not significantly different in the Noni group when compared to the controls.Conclusion. Noni did not show a reduction in menstrual pain or bleeding when compared to placebo. |
| Databáze: | OpenAIRE |
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