Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome
| Autor: | Niels Klement, Andreas Herrmann, H. Bauke Albada, Eyal Golub, Qing Liu, Itamar Willner, Jan Willem de Vries |
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| Přispěvatelé: | Intelligent Systems, Polymer Chemistry and Bioengineering, Nanotechnology and Biophysics in Medicine (NANOBIOMED) |
| Rok vydání: | 2016 |
| Předmět: |
Stereochemistry
Dopamine Aptamer Deoxyribozyme Supramolecular chemistry macromolecular substances 010402 general chemistry 01 natural sciences Micelle Catalysis Journal Article Materials Chemistry medicine Life Science Indolequinones Micelles 010405 organic chemistry Chemistry Organic Chemistry technology industry and agriculture Metals and Alloys Substrate (chemistry) General Chemistry Organische Chemie Combinatorial chemistry 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Catalytic oxidation Ceramics and Composites lipids (amino acids peptides and proteins) Oxidation-Reduction medicine.drug |
| Zdroj: | Chemical Communications 52 (2016) 32 Chemical Communications, 52(32), 5561-5564 Chemical communications (Cambridge, England), 52(32), 5561-5564. ROYAL SOC CHEMISTRY |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c6cc01115b |
| Popis: | Lipidated DNAzymes or a lipidated Cu(ii)-complex and lipidated aptamer sequences form supramolecular assemblies of micellar nucleoapzymes for the enhanced oxidation of dopamine to aminochrome. The catalytic functions of the micellar nucleoapzymes are attributed to the concentration of the substrate, using the aptamer units, in close proximity to the active sites. |
| Databáze: | OpenAIRE |
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