The role of perineal application of prophylactic negative-pressure wound therapy for prevention of wound-related complications after abdomino-perineal resection: a systematic review
| Autor: | Ziad Abbassi, Nicolas C. Buchs, Jeremy Meyer, Elin Roos, Christian Toso, Frédéric Ris |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Wound therapy medicine.medical_treatment MEDLINE Review Perineum Negative-pressure wound therapy Internal medicine medicine Humans Surgical Wound Infection Rectal cancer Wound Healing Proctectomy integumentary system business.industry Wound dehiscence Rectal Neoplasms Gastroenterology Hepatology Abdomino perineal resection medicine.disease Colorectal cancer Surgery Lower incidence Perineal infection business Infection Surgical site infection Abdomino-perineal amputation Negative-Pressure Wound Therapy Abdomino-perineal resection |
| Zdroj: | International Journal of Colorectal Disease |
| ISSN: | 1432-1262 0179-1958 |
| Popis: | Background Closed perineal wounds often fail to heal by primary intention after abdomino-perineal resection (APR) and are often complicated by surgical site infection (SSI) and/or wound dehiscence. Recent evidence showed encouraging results of prophylactic negative-pressure wound therapy (pNPWT) for prevention of wound-related complications in surgery. Our objective was to gather and discuss the early existing literature regarding the use of pNPWT to prevent wound-related complications on perineal wounds after APR. Methods Medline, Embase, and Web of Science were searched for original publications and congress abstracts reporting the use of pNPWT after APR on closed perineal wounds. Results Seven publications were included for analysis. Two publications reported significantly lower incidence of SSI in pNPWT patients than in controls with a risk reduction of about 25–30%. Two other publications described similar incidences of SSI between the two groups of patients but described SSI in pNPWT patients to be less severe. One study reported significantly lower incidence of wound dehiscence in pNPWT patients than in controls. Conclusion The largest non-randomized studies investigating the effect of pNPWT on the prevention of wound-related complications after APR showed encouraging results in terms of reduction of SSI and wound dehiscence that deserve further investigation and confirmation. |
| Databáze: | OpenAIRE |
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