Nepeta cataria L. var. citriodora (Becker) increases penile erection in rats
| Autor: | Tatiana Marisis Giovani, Thiago Berti Kirsten, João Henrique G. Lago, Cristina de Oliveira Massoco, Maria Martha Bernardi |
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| Přispěvatelé: | Universidade de São Paulo (USP), Univ Paulista, Universidade Federal de São Paulo (UNIFESP) |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Male
Sexual behavior medicine.medical_specialty Time Factors AGENTES DOPAMINÉRGICOS Dopamine Agents Nepeta cataria Motor Activity Open field Sexual Behavior Animal Catnip Internal medicine Drug Discovery Male rats medicine Animals Rats Wistar Pharmacology Plants Medicinal CATS biology Penile erection business.industry Dopaminergic biology.organism_classification Rats Motor coordination Plant Leaves Endocrinology Anesthesia Nepeta Sexual motivation Female Yawning Plant Preparations business After treatment |
| Zdroj: | Repositório Institucional da UNIFESP Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Ethnopharmacological relevance: Nepeta cataria (NC), catnip, induces pleasure in cats and humans. Aim of the study: Because sexual behavior is involved in pleasure, the effect of NC on sexual behavior and penile erection was evaluated in male rats that were acutely fed chow enriched with 10% NC leaves. Further, yawning was monitored because we previously demonstrated that NC modifies dopaminergic-related behaviors and that sexual behavior is closely linked with the dopaminergic system. the general activity and the motor coordination were examined to investigate the possible motor and emotional interferences of the sexual performance.Material and methods: Male rats of the NC group received for a 4 h period the chow enriched with 10% NC leaves while the control groups received regular chow. Fifteen min after the end of the 4 h period of NC feeding the sexual behavior, apomorphine-induced penile erection and motor coordination were observed; the general activity in the open field was assessed 0, 15, 30 and 60 min after treatment.Results: NC treatment increased male rat's penile erection. A slightly facilitation on male rat sexual behavior and a decreased in general activity of NC treated rats were observed. No effects on motor coordination and yawning episodes were detected by the NC treatment.Conclusions: It was suggested that NC increases penile erection and slightly improves male rat sexual behavior by an action on dopaminergic systems. (C) 2011 Elsevier Ireland Ltd. All rights reserved. Univ São Paulo, Sch Vet Med, Dept Pathol, BR-05508000 São Paulo, Brazil Univ Paulista, Hlth Sci Inst, São Paulo, Brazil Universidade Federal de São Paulo, Dept Ciencias Exatas & Terra, Diadema, SP, Brazil Universidade Federal de São Paulo, Dept Ciencias Exatas & Terra, Diadema, SP, Brazil CNPq: 301739/2007-2 Web of Science |
| Databáze: | OpenAIRE |
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