Supplementary Figures S1-S12 from Natural Product Vibsanin A Induces Differentiation of Myeloid Leukemia Cells through PKC Activation

Autor: Yu-Wen Cong, Qin-Shi Zhao, Qing-Liang Luo, Li-Sheng Wang, Jian-Nan Feng, Bo Dong, Xiao-Lan Liu, Guo-Lin Xiong, Shuang Xing, Wen-Bing Zhou, Ya-Jun Shan, Yu Cui, Yan-Feng Zhang, Wen-Feng Sun, Lin Wang, Yu Jing, Xing Shen, Li-Mei Wang, He Xiao, Zu-Yin Yu
Rok vydání: 2023
DOI: 10.1158/0008-5472.22411308
Popis: Differentiation induction activity of vibsanine A and its analogues on HL-60 Cells (S1); Characterization of differentiation-inducing activity of vibsanine A (S2); Vibsanine A-induced growth inhibition of myeloid leukemia cells (S3); Gene expression profiles in HL-60 cells (S4); Downregulation of PKC isozymes induced by vibsanine A and PMA (S5); Effect of different PKC inhibitors on the PMA-induced differentiation (S6); [3H]PDBu Binding (S7); The 3-D complex structures of PKC isoforms and vibsanine A (S8); Ectopic c-Myc expression blocked G1 cell cycle arrest by vibsanine A (S9); Ectopic c-Myc expression effectively inhibited cellular differentiation by vibsanine A in infected NB4 cells (S10); Effect of vibsanine A treatment on the body weight of mouse xenograft models of AML (S11); Effect of vibsanine A on PMA-induced inflammatory responses in CD-1 mice (S12).
Databáze: OpenAIRE