The spectrum of nasal involvement in systemic lupus erythematosus and its association with the disease activity
| Autor: | Rajalingham Sakthiswary, Syahrul Sazliyana Shaharir, A H Haizlene, K H Yusof, B S Gendeh, K A Kusyairi |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Nasal congestion Severity of Illness Index Gastroenterology Muscle hypertrophy Disease activity Young Adult 03 medical and health sciences 0302 clinical medicine Rheumatology Predictive Value of Tests Risk Factors Internal medicine Nose Diseases otorhinolaryngologic diseases Mucositis medicine Humans Lupus Erythematosus Systemic skin and connective tissue diseases 030223 otorhinolaryngology Nose Aged 030203 arthritis & rheumatology Systemic lupus erythematosus Torus palatinus business.industry Endoscopy Middle Aged respiratory system medicine.disease Surgery Deviated nasal septum Nasal Mucosa Cross-Sectional Studies medicine.anatomical_structure Female medicine.symptom business |
| Zdroj: | Lupus. 25:520-524 |
| ISSN: | 1477-0962 0961-2033 |
| DOI: | 10.1177/0961203315622279 |
| Popis: | The purpose of this study was to determine the spectrum of nasal involvement in systemic lupus erythematosus (SLE) and its association with the disease activity of SLE based on the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). This was a cross-sectional and observational study involving 73 stable SLE patients. All subjects were evaluated for the SLEDAI scores and had nasal endoscopic examination. The most commonly reported symptom was nasal congestion (31.5%) followed by nasal itchiness (26.0%), runny nose (20.5%) and nasal dryness (19.2%). Almost half (42.9%) of the subjects had nasal mucosal abnormalities, which included mucositis, crusting, ulceration, bifid middle turbinate, septal spur, Jacobson’s organ, deviated nasal septum, bilateral inferior turbinate hypertrophy, everted uncinate process, nasopharynx cleft and torus palatinus. The median SLEDAI score for subjects with nasal symptoms was significantly higher than subjects without nasal symptoms ( p |
| Databáze: | OpenAIRE |
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