MOESM1 of Advanced glycation end products induce brain-derived neurotrophic factor release from human platelets through the Src-family kinase activation

Autor: Furukawa, Kazuo, Fuse, Ichiro, Iwakura, Yuriko, Sotoyama, Hidekazu, Hanyu, Osamu, Nawa, Hiroyuki, Sone, Hirohito, Takei, Nobuyuki
Rok vydání: 2017
Předmět:
DOI: 10.6084/m9.figshare.c.3686854_d1.v1
Popis: Additional file 1: Figure S1. Scatter plot of BDNF levels in whole blood, serum and platelets (1 × 108 cells) (n = 10). Table S1. The blood information of the volunteers. The blood samples were sent to SRL Inc, Japan. and fasting plasma glucose (FPG), fasting immunoreactive insulin (FIRI), HbA1c was analyzed at SRL. The homeostasis model assessment of insulin resistance (HOMA-IR) was calculated from FIRI and FPG by the following equation: HOMA-R = FIRI (mU/l) × FPG (mmol/l)/22.5. Data are means ± SEM. Figure S2. BDNF release at higher AGE concentrations (100 μg–1 mg/ml AGE). Data are presented as means ± SEM (n = 8). Statistical analyses were performed by SPSS one-way ANOVA. *p
Databáze: OpenAIRE