Cutaneous leishmaniasis (Leishmania major infection) in Dutch troops deployed in northern Afghanistan: epidemiology, clinical aspects, and treatment
| Autor: | William R. Faber, Michèle van Vugt, Peter J. de Vries, Alex C. Krull, Allard van der Sluis, Tjalling Leenstra, Piet A. Kager, Henry J. C. de Vries, Wendy F. van der Meide, Aldert Bart, Jim E. Zeegelaar, Pieter-Paul A. M. van Thiel, Henk D. F. H. Schallig, Tom van Gool |
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| Přispěvatelé: | Infectious diseases, AII - Amsterdam institute for Infection and Immunity, APH - Amsterdam Public Health, Dermatology, Medical Microbiology and Infection Prevention, KIT: Biomedical Research |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.medical_treatment Phosphorylcholine Attack rate Antiprotozoal Agents Leishmaniasis Cutaneous Cryotherapy Intralesional injections Cutaneous leishmaniasis Virology Internal medicine Epidemiology Medicine Humans Leishmania major Netherlands Miltefosine biology business.industry Afghanistan Articles biology.organism_classification medicine.disease Surgery Infectious Diseases Military Personnel Parasitology business Field conditions medicine.drug |
| Zdroj: | American journal of tropical medicine and hygiene, 83(6), 1295-1300. American Society of Tropical Medicine and Hygiene |
| ISSN: | 1476-1645 0002-9637 |
| Popis: | Cutaneous leishmaniasis caused by Leishmania major infection affected 172 (18.3%) of 938 Dutch military troops deployed in northern Afghanistan in 2005. The high attack rate was a result of initial insufficient availability of means of prevention and insufficient adherence to preventive measures. At presentation, the lymphatic system was involved in 24.8%. Treatment with intralesional injections of antimony with or without cryotherapy was satisfactory, but 19.5% of patients received secondary treatment with miltefosine. Six months after treatment, 128 (77.1%) of 166 treated patients were cured, 16 (9.6%) were lost to follow-up, and 22 (13.3%) already experienced cure at six weeks but were not seen at six months. Natural evolution played a role in this observational study, which showed cure of all patients seen at six months. In general, management of cutaneous leishmaniasis was feasible under field conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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