| Autor: |
David O. Williams, Steven E. Reinert, Mary Jane McDonald, George R. McKendall |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Journal of the American College of Cardiology. 25(2):206A-207A |
| ISSN: |
0735-1097 |
| DOI: |
10.1016/0735-1097(95)92315-v |
| Popis: |
In order to determine whether expanding use of thrombolytic therapy (TT) has influenced overall acute myocardial infarction (AMI) outcome, we evaluated 1205 consecutive AMI patients (pts) with ST segment elevation who presented from 1989 to 1993. Baseline characteristics of age (64 ± 13 years), gender (70% male), and TT contraindications (38%) did not vary from year to year. Characteristics of pts treated with TT by year are shown. 1989 1990 1991 1992 1993 P TT treated % (n) 42 (87) 45(113) 45(104) 63(156) 65(175) 0.0001 Mean age (yrs) 58 ± 11 58 ± 11 57 ± 13 60 ± 11 60 ± 13 0190 Age g 76(%) 2.3 1.0 1.9 7.7 9.1 0003 Male (%) 75 75 85 73 71 0150 Symptom duration. min 0010 mean ± SD 87 ± 57 106 ± 96 108 ± 104 119 ± 97 135 ± 112 range 12-307 17–676 15–657 12-740 16–609 median 69 80 80 94 103 AMI mortality (%) TT treated pts 83 7.1 53 7.7 4.6 0350 No IT pts 21.8 16.2 15.2 139 208 0.447 All pts 160 12.0 109 10.0 10.3 0.050 Utilization of TT increased significantly by treating more pts g 76 years and those with longer symptom duration. Trend analysis demonstrates that mortality in AMI pts treated with TT did not change significantly from year to year. Overall AMI mortality, however, decreased significantly with expanding use of TT. Thus, use of TT can be increased by treating more elderly pts and those with longer symptom duration. Expanding use of TT is associated with reduction in overall AMI mortality. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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