Tendon Graft Healing in Multiligament Reconstructed Knee Detected by FDG-PET/CT: a Pilot Study
| Autor: | Sami Kajander, S. Alihanka, Ari Itälä, J. Kemppainen, J. Kosola, Juha O. Ranne |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Adolescent Anterior cruciate ligament reconstruction medicine.medical_treatment Aftercare Posterior Cruciate Ligament Reconstruction Pilot Projects Knee Injuries 030218 nuclear medicine & medical imaging Tendons Young Adult 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Region of interest Positron Emission Tomography Computed Tomography medicine Humans Tendon graft Retrospective Studies Fluorodeoxyglucose ta3126 Wound Healing 030222 orthopedics Anterior Cruciate Ligament Reconstruction medicine.diagnostic_test business.industry Graft Survival Magnetic resonance imaging Patient population Feasibility Studies Female Surgery Fdg pet ct Tomography Radiopharmaceuticals business Nuclear medicine Follow-Up Studies medicine.drug |
| Zdroj: | Scandinavian Journal of Surgery. 105(2):133-138 |
| ISSN: | 1457-4969 |
| Popis: | Background and Aims: The detection of graft viability is challenging in the multiligament reconstructed knee. Magnetic resonance imaging gives structural information but lacks the capability to assess biological activity of the grafts. 18F-labeled fluorodeoxyglucose positron emission tomography combined with computer tomography is shown to be a sensitive method for imaging tissue metabolism and viability. The aim of the present study was to evaluate the feasibility of fluorodeoxyglucose positron emission tomography combined with computer tomography imaging in the detection of the replacement graft metabolism in multiligament reconstructed knees. Materials and Methods: Seven patients (17–44 years) with multiligament reconstructed knee underwent fluorodeoxyglucose positron emission tomography combined with computer tomography to evaluate the biological activity of replacement grafts. The degree of fluorodeoxyglucose uptake reported as standard uptake values from the region of interest was analyzed 3–24 months postoperatively. Results: In all patients, the fluorodeoxyglucose positron emission tomography combined with computer tomography showed increased fluorodeoxyglucose uptake in all replacement grafts at different follow-up time points. Furthermore, fluorodeoxyglucose was higher at femoral condyles of operated knees compared to contralateral reference values. Conclusion: This pilot study shows a significant increase in tendon graft metabolism during two first years of postoperative healing. The fluorodeoxyglucose positron emission tomography combined with computer tomography imaging seems to be adequate method of assessment of graft metabolism and viability during postoperative healing. The clinical value of fluorodeoxyglucose positron emission tomography combined with computer tomography imaging, however, warrants further evaluation with longitudinal studies with a larger patient population. |
| Databáze: | OpenAIRE |
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