Transference of reference intervals in the validation of automated chemiluminescent immunoassays on a new platform
| Autor: | Anne Thompson, Bruce Gaumond, Ann Jacob, Michael Lynch, Holly Leonard, John Kilroy, Thomas Jackson |
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| Rok vydání: | 1998 |
| Předmět: |
Immunoassay
Computer science business.industry Group method of data handling Biochemistry (medical) Clinical Biochemistry Reproducibility of Results Interval (mathematics) Thyroid Function Tests Automation Boundary values Reliability engineering Reference intervals Fertility Reference Values Component (UML) Luminescent Measurements Biomarkers Tumor Work flow Humans Regression Analysis business Automated immunoassay Biomarkers |
| Zdroj: | Clinical chemistry. 44(9) |
| ISSN: | 0009-9147 |
| Popis: | Integrating highly evolved automated immunoassay platforms into the laboratory provides long-term advantages such as improvements in work flow, performance, and data handling. However, to make the transition from a current platform to a new platform the end user is often required to revise reference intervals, a time-consuming and often tedious process. According to the guidelines of the NCCLS (C28-A) (1) , transference may be used to confirm that an established reference interval can be applied between two methods that show substantially the same precision and interferences, use comparable calibrators, and yield comparable values. Establishing transference was a fundamental component of the strategy for validating ACS:180® thyroid, fertility, and oncology assays on the ACS:CentaurTM system. Laboratories currently using the ACS:180 system will find introducing an ACS:Centaur system simpler because the reference intervals they established on the ACS:180 system apply to the ACS:Centaur system. A minimum of three ACS:180 systems and … |
| Databáze: | OpenAIRE |
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