Antimicrobial Stewardship Strategies Including Point-of-Care Testing (POCT) for Pediatric Patients with Upper-Respiratory-Tract Infections in Primary Care: A Systematic Review of Economic Evaluations
| Autor: | Costanza Vicentini, Lorenzo Vola, Christian Previti, Valerio Brescia, Francesca Dal Mas, Carla Maria Zotti, Fabrizio Bert |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Microbiology (medical)
C-reactive protein tests children health–economic evaluations nucleic acid amplification tests point-of-care tests primary care rapid antigen-detection tests upper-respiratory-tract infections Settore MED/42 - Igiene Generale e Applicata Biochemistry Microbiology Infectious Diseases Settore SECS-P/07 - Economia Aziendale Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics |
| Zdroj: | Antibiotics (Basel, Switzerland). 11(8) |
| ISSN: | 2079-6382 |
| Popis: | Upper-respiratory-tract infections (URTIs) are among the main causes of antibiotic prescriptions in pediatric patients. Over one-third of all antibiotic prescriptions for URTIs in children are estimated to be inappropriate, as the majority of URTIs are caused by viral agents. Several strategies, including clinical scoring algorithms and different point-of-care tests (POCTs) have been developed to help discriminate bacterial from viral URTIs in the outpatient clinical setting. A systematic review of the literature was conducted following PRISMA guidelines with the objective of summarizing evidence from health–economic evaluations on the use of POCT for URTIs in pediatric outpatients. A total of 3375 records identified from four databases and other sources were screened, of which 8 met the inclusion criteria. Four studies were classified as being of high reporting quality, and three were of medium quality. Five out of eight studies concluded in favor of strategies that included POCTs, with an additional study finding several POCTs to be cost-effective compared to usual care but over an acceptable WTP threshold. This review found POCT could be a valuable tool for antimicrobial stewardship strategies targeted towards childhood URTIs in primary care. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|