Gq-Gi-PLCβ in cells: More than the sum of its reconstituted parts
| Autor: | Sarthak Reddy, Michael A. Hale, Thomas M. Wilkie |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Physiology Cell Phospholipase C beta macromolecular substances Calcium mobilization 03 medical and health sciences 0302 clinical medicine parasitic diseases medicine Calcium Signaling Molecular Biology G protein-coupled receptor Calcium signaling biology Chemistry Cell Biology In vitro Cell biology 030104 developmental biology medicine.anatomical_structure Gq alpha subunit biology.protein GTP-Binding Protein alpha Subunits Gq-G11 Calcium Heterotrimeric G Protein Subunit RGS Proteins 030217 neurology & neurosurgery |
| Zdroj: | Cell calcium. 94 |
| ISSN: | 1532-1991 |
| Popis: | The recent paper by Pfeil et al., "Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs", opens another path from biochemical in vitro reconstitution to understanding the complex regulation of calcium signaling inside the cell. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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