Sperm Chromatin Structure Assay (SCSA)

Autor: Madhu Shivhare1, Nidhi Srivastava 2and Reshma Jain 3
Rok vydání: 2023
Předmět:
DOI: 10.5281/zenodo.8132131
Popis: To Read the full Article, Download from the main website www.thescienceworld.net The Sperm Chromatin Structure Assay (SCSA) is a demonstrative procedure utilized to distinguish strange sperm with critical DNA discontinuity (Ohsu, 2021). Initially presented by Evenson in 1980, this examine uses stream cytometry to recognize the weakness of sperm DNA to corrosive actuated denaturation DNA in situ (Evenson and Donald, 2016). The SCSA evaluates the degree of sperm DNA discontinuity brought about by both inborn and outward factors and measures the level of fracture as the DNA Fracture File (DFI). The utilizations of SCSA include the assessment of male barrenness and subfertility, toxicology studies, and appraisal of research facility semen test quality.
Databáze: OpenAIRE