Heart Donation From Donors After Controlled Circulatory Death
| Autor: | Laura Anguela-Calvet, Steven Tsui, Fabrizio Sbraga, José González-Costello, Eva Oliver-Juan, Gabriel Moreno-Gonzalez |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Tissue and Organ Procurement Ischemia 030230 surgery Donor Selection 03 medical and health sciences 0302 clinical medicine Cause of Death medicine Humans Intensive care medicine Donor pool Heart Failure Transplantation business.industry medicine.disease Circulatory death Tissue Donors Perfusion Treatment Outcome Heart failure Donation Tissue and Organ Harvesting Heart Transplantation 030211 gastroenterology & hepatology business Reperfusion injury |
| Zdroj: | Transplantation. 105:1482-1491 |
| ISSN: | 0041-1337 |
| Popis: | The gold-standard therapy for advanced-stage heart failure is cardiac transplantation. Since the first heart transplant in 1967, the majority of hearts transplanted came from brain death donors. Nevertheless, in recent years, the option of donation after circulatory death (DCD) is gaining importance to increase donor pool. Currently, heart-transplant programs using controlled donation after circulatory death (cDCD) have been implemented in the United Kingdom, Belgium, Australia, United States of America, and, recently, in Spain. In this article, we performed a concise review of the literature in heart cDCD; we summarize the pathophysiology involved in ischemia and reperfusion injury during this process, the different techniques of heart retrieval in cDCD donors, and the strategies that can be used to minimize the damage during retrieval and until transplantation. Heart transplant using DCD hearts is in continuous improvement and must be implemented in experienced cardiac transplant centers. |
| Databáze: | OpenAIRE |
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