Thromboelastography‐guided therapy improves patient blood management and certain clinical outcomes in elective cardiac and liver surgery and emergency resuscitation: A systematic review and analysis
| Autor: | Angela Sauaia, Hardean E. Achneck, Jan Hartmann, Ernest E. Moore, João D. Dias |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Blood management
Point-of-Care Systems Resuscitation Blood Loss Surgical 030204 cardiovascular system & hematology elective surgical procedures law.invention blood coagulation 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Blood product law Outcome Assessment Health Care Medicine Humans Blood Transfusion Elective surgery Cardiac Surgical Procedures Digestive System Surgical Procedures medicine.diagnostic_test business.industry HAEMOSTASIS thromboelastography Hematology Perioperative Original Articles Intensive care unit Thromboelastography Hemostasis Surgical 3. Good health Thrombelastography cardiovascular surgical procedures Anesthesia emergency treatment Original Article Elective Surgical Procedure business |
| Zdroj: | Journal of Thrombosis and Haemostasis |
| ISSN: | 1538-7836 1538-7933 |
| Popis: | Essentials TEG‐guided therapy has been shown to be valuable in a number of surgical settings.This systematic review and analysis specifically evaluated the effects of TEG‐guided therapy.TEG‐guided therapy can improve blood product utilization and enhance resource management.Use of TEG improved key patient outcomes, including bleed rate, length of stay and mortality. Background Thromboelastography (TEG 5000 and 6s Thrombelastograph Hemostasis Analyzer; Haemonetics) is a point‐of‐care system designed to monitor and analyze the entire coagulation process in real time. TEG‐guided therapy has been shown to be valuable in a variety of surgical settings. Objective To conduct an analysis of published clinical trials to evaluate the effects of TEG‐guided transfusion for the management of perioperative bleeding on patient outcomes. Patients/Methods We searched MEDLINE (PubMed) and EMBASE for original articles reporting studies using TEG vs controls in a perioperative setting for inclusion in this systematic review. We identified nine eligible randomized controlled trials (RCTs) in two elective surgery settings (cardiac surgery and liver surgery), but only one RCT in the emergency setting. Results In the elective surgery study meta‐analysis, platelet (P = 0.004), plasma (P |
| Databáze: | OpenAIRE |
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