Microfabricated cantilevers for measurement of subcellular and molecular forces
Autor: | Harold G. Craighead, Gerald H. Pollack, D.H. Lilienfeld, Mark E. Fauver, Dwayne L. Dunaway |
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Rok vydání: | 1998 |
Předmět: |
Silicon
Materials science Cantilever business.product_category Surface Properties Transducers Biomedical Engineering Nanotechnology Young's modulus macromolecular substances Fluorescence symbols.namesake Myofibrils Materials Testing medicine Microscopy Phase-Contrast Wafer Composite material Reproducibility Lever Microscopy Video technology industry and agriculture Reproducibility of Results Stiffness Cell Biology Equipment Design Elasticity Transducer Nanolithography Calibration symbols medicine.symptom business |
Zdroj: | IEEE Transactions on Biomedical Engineering. 45:891-898 |
ISSN: | 0018-9294 |
DOI: | 10.1109/10.686797 |
Popis: | We present two new microfabricated cantilever-beam force transducers. The transducers were fabricated from thin silicon-nitride films, and were used respectively to measure forces generated by two small-muscle preparations: the single myofibril, and the single actin filament in contact with a myosin-coated surface. A simple resonance method was developed to characterize the transducers. Because of the high reproducibility of lever dimensions and the consistency of the modulus of elasticity, few calibration measurements sufficed to characterize the stiffness of all the levers on a single wafer. |
Databáze: | OpenAIRE |
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