Pure yolk sac tumour, post-pubertal type, arising from cryptorchid testes
| Autor: | Jeffrey Monteiro, Shekhar Gouda, Hemant Janugade |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Pathology medicine.medical_specialty food.ingredient Exploratory laparotomy medicine.medical_treatment 030232 urology & nephrology Glypican 3 surgical oncology 03 medical and health sciences Cytokeratin 0302 clinical medicine food Testicular Neoplasms Rare Disease Yolk Cryptorchidism medicine Humans Yolk sac business.industry Endodermal Sinus Tumor General Medicine Middle Aged Pelvic cavity medicine.anatomical_structure 030220 oncology & carcinogenesis oncology Immunohistochemistry Abdomen pathology Tomography X-Ray Computed business |
| Zdroj: | BMJ Case Reports |
| ISSN: | 1757-790X |
| Popis: | Yolk sac tumour (YST), the most common germ cell tumour (GCT) in infants and children, accounts for 80% of GCTs in this age group.1It is observed in only 2.4% of adult patients in their pure form since up to 42% of mixed GCTs have some component of the yolk sac.2We present a 46-year-old cryptorchid man who presented with complaints of abdominal lump, pain and altered bowel habits since 1 month. CT scan of the abdomen revealed a mass arising from the pelvic cavity with feeders predominantly from the left gonadal vessel. Mass was excised via exploratory laparotomy and sent for histological examination. Microscopic examination was suggestive of pure YST. Immunohistochemistry stained positive for cytokeratin, placental-like alkaline phosphatase, Glypican 3 and alpha fetoprotein. The patient succumbed prior to commencing chemotherapy. Pure YSTs of post-pubertal origins are extremely rare and are more aggressive than their prepubertal counterparts. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|