Assessing the Genetic Landscape of Animal Behavior
| Autor: | Ryan A. York |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Developmental and Behavioral Genetics
0301 basic medicine media_common.quotation_subject Quantitative Trait Loci Inheritance Patterns Genomics Genome-wide association study Investigations Biology Quantitative trait locus behavioral evolution Courtship 03 medical and health sciences Quantitative Trait Heritable 0302 clinical medicine Phylogenetics Genetic variation Genetics GWAS Animals behavior genetics Genetic Association Studies Phylogeny Behavioural genetics media_common Behavior Animal Bayes Theorem 030104 developmental biology Drosophila 030217 neurology & neurosurgery Genome-Wide Association Study |
| Zdroj: | Genetics |
| ISSN: | 1943-2631 |
| DOI: | 10.1534/genetics.118.300712 |
| Popis: | Recent years have seen an increase in studies that associate genomic loci with behavioral variation both within and across animal species. Ryan York compiles and analyzes over 1,000 of these loci, finding that the genetic... Although most animal behaviors are associated with some form of heritable genetic variation, we do not yet understand how genes sculpt behavior across evolution, either directly or indirectly. To address this, I here compile a data set comprised of over 1000 genomic loci representing a spectrum of behavioral variation across animal taxa. Comparative analyses reveal that courtship and feeding behaviors are associated with genomic regions of significantly greater effect than other traits, on average threefold greater than other behaviors. Investigations of whole-genome sequencing and phenotypic data for 87 behavioral traits from the Drosophila Genetics Reference Panel indicate that courtship and feeding behaviors have significantly greater genetic contributions and that, in general, behavioral traits overlap little in individual base pairs but increasingly interact at the levels of genes and traits. These results provide evidence that different types of behavior are associated with variable genetic bases and suggest that, across animal evolution, the genetic landscape of behavior is more rugged, yet predictable, than previously thought. |
| Databáze: | OpenAIRE |
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