Beta 2-adrenoceptor agonists and thyroid hormones

Autor: T L Svendsen, J. P. Kampmann, J E Mølholm Hansen, L. Skovsted
Rok vydání: 1982
Předmět:
Zdroj: British Journal of Clinical Pharmacology. 14:447-448
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1982.tb02006.x
Popis: The potential influence of the selective beta 2-adrenoceptor agonist terbutaline on the serum concentration of the thyroid hormones in humans was studied in 11 healthy euthyroid subjects. Five served as a control group without medication while six received 5 mg terbutaline three times daily for 2 weeks. No significant differences were found between the two groups by measuring the serum concentrations of thyroxine, triiodothyronine, reverse triiodothyronine and resin-triiodothyronine uptake. The use of a beta 2-adrenergic receptor stimulating drug is relatively contraindicated in untreated thyrotoxicosis. This recommendation is based upon a summation of clinical adverse reactions and not due to an effect on the serum concentrations of thyroid hormones.
Databáze: OpenAIRE