Time-dependent roles of adolescent- and adult-born dentate granule neurons in spatial learning
| Autor: | Shaoyu Ge, Marie-Françoise Montaron, Nuria Masachs, Sophie Tronel, Valérie Lemaire, Nicolas Blin, Fanny Farrugia, Daniela Cota, Cyril Herry, Wilfrid Mazier, Djoher Nora Abrous, Véronique Deroche-Gamonet, Vanessa Charrier |
|---|---|
| Přispěvatelé: | INSERM, Neurocentre Magendie, U1215, Physiopathologie de la Plasticité Neuronale, F-33000 Bordeaux, France, Institut National de la Santé et de la Recherche Médicale (INSERM), State University of New York (SUNY), tronel, sophie, Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale (U1215 Inserm - UB), Université de Bordeaux (UB)-Institut François Magendie-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0303 health sciences
Dentate gyrus [SCCO.NEUR]Cognitive science/Neuroscience [SDV]Life Sciences [q-bio] [SCCO.NEUR] Cognitive science/Neuroscience Cognition Biology Development 03 medical and health sciences 0302 clinical medicine Spatial memory nervous system Spatial learning Rat Optogenetic Neuroscience 030217 neurology & neurosurgery 030304 developmental biology |
| Popis: | SUMMARYThe dentate gyrus presents the peculiarity to be formed after birth in rodents. Adolescence is a very sensitive period during which cognitive competences are programmed. We investigated and compared the role of dentate neurons born during adolescence or generated during adulthood. We demonstrated that the ontogenetic stage of dentate neurons in relation to when they are generated dictates their participation in memory processes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|