Malignant central airway obstruction
| Autor: | Lakshmi Mudambi, Russell J. Miller, Georgie A. Eapen |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty business.industry medicine.medical_treatment Brachytherapy Cryotherapy Review Article Disease medicine.disease Debulking Surgery Diagnostic modalities 03 medical and health sciences 0302 clinical medicine 030228 respiratory system 030220 oncology & carcinogenesis medicine Central airway Intensive care medicine business Airway Lung cancer |
| Zdroj: | Journal of Thoracic Disease. 9:S1087-S1110 |
| ISSN: | 2077-6624 2072-1439 |
| DOI: | 10.21037/jtd.2017.07.27 |
| Popis: | This review comprehensively describes recent advances in the management of malignant central airway obstruction (CAO). Malignant CAO can be a dramatic and devastating manifestation of primary lung cancer or metastatic disease. A variety of diagnostic modalities are available to provide valuable information to plan a therapeutic intervention. Clinical heterogeneity in the presentation of malignant CAO provides opportunities to adapt and utilize endoscopic technology and tools in many ways. Mechanical debulking, thermal tools, cryotherapy and airway stents are methods and instruments used to rapidly restore airway patency. Delayed bronchoscopic methods, such as photodynamic therapy (PDT) and brachytherapy can also be utilized in specific non-emergent situations to establish airway patency. Although data regarding the success and complications of therapeutic interventions are retrospective and characterized by clinical and outcome measure variability, the symptoms of malignant CAO can often be successfully palliated. Assessment of risks and benefits of interventions in each individual patient during the decision-making process forms the critical foundation of the management of malignant CAO. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|