The prevalence and correlates of hepatitis C virus (HCV) infection and HCV–HIV co-infection in a community sample of gay and bisexual men
| Autor: | Jeffrey P. Aguinaldo, Ann N. Burchell, Ted Myers, Liviana Calzavara, Carol Swantee, Dan Allman, Robert S. Remis, Kunyong Xu |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Sexual transmission Cross-sectional study Sexual Behavior Prevalence HIV Infections Men who have sex with men Acquired immunodeficiency syndrome (AIDS) Risk Factors Surveys and Questionnaires Internal medicine medicine Humans Needle Sharing MSM Homosexuality Male Needle sharing business.industry HIV virus diseases General Medicine Odds ratio Hepatitis C medicine.disease digestive system diseases Gay and bisexual Cross-Sectional Studies Infectious Diseases HCV Immunology Correlates Bisexuality business |
| Zdroj: | International Journal of Infectious Diseases. 13:730-739 |
| ISSN: | 1201-9712 |
| DOI: | 10.1016/j.ijid.2008.11.015 |
| Popis: | Summary Objective To describe hepatitis C virus (HCV) and HIV prevalence and co-infection, and to examine variables associated with infection in a community sample of men who have sex with men (MSM). Methods Data were from an anonymous, cross-sectional study ( N =5080) in Canada. Men self-completed a questionnaire and provided an optional saliva specimen for HCV and HIV testing. Polytomous logistic regressions identified variables associated with HCV, HIV, and HCV–HIV co-infection. Results The prevalences of HCV, HIV, and HCV–HIV co-infection were 1.9%, 9.0%, and 0.7%, respectively. The greatest contribution to HCV (odds ratio (OR) 23.66, 95% confidence interval (CI) 9.69–57.73) and HCV–HIV co-infection (OR 26.76, 95% CI 7.97–89.80) was injection drug use. Sexual behaviors and proxies were associated with HIV but not HCV infection. Conclusions Results suggest there are subgroups of MSM at risk for HCV. While sexual transmission of HCV was not ruled out, the predominant risk was needle sharing. The greater prevalence of HCV among HIV-positive men suggests the need for greater vigilance in the detection of HCV in this group. |
| Databáze: | OpenAIRE |
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