Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity
| Autor: | N. Markou, Chryssa Pourzitaki, M. Sileli, Charalambos Gogos, E. Aimoniotou, Panagiotis Halvatsiotis, Panagiotis Koulouvaris, George Dimopoulos, D. Velissaris, Anastasia Kotanidou, Kimon Tzannis, Eleni Magira, A Armaganidis, G. Konstandopoulou, E. Gkeka, N. Kapravelos, Aristotelis Bamias, T. Zafeiridis, E. Stefanatou, Edison Jahaj, G. Vlachogianni, S. Papoti, Apostolos Komnos, Maria Theodorakopoulou |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty obesity critically ill Critical Illness Endocrinology Diabetes and Metabolism Intensive Care Unit Pneumonia Viral 030209 endocrinology & metabolism Type 2 diabetes Comorbidity Article law.invention 03 medical and health sciences Betacoronavirus 0302 clinical medicine Endocrinology law Risk Factors Diabetes mellitus medicine Diabetes Mellitus Internal Medicine Humans 030212 general & internal medicine Risk factor Survival rate Pandemics Type-2 diabetes Aged Retrospective Studies Greece business.industry SARS-CoV-2 COVID-19 Retrospective cohort study General Medicine Middle Aged medicine.disease Prognosis Obesity Intensive care unit Hospitalization Survival Rate Female business Coronavirus Infections |
| Zdroj: | Diabetes Research and Clinical Practice |
| ISSN: | 0168-8227 |
| DOI: | 10.1016/j.diabres.2020.108331 |
| Popis: | Highlights • Critically ill Covid-19 patients with type-2 diabetes show decreased survival rate. • Obese critically ill Covid-19 pneumonia patients are more often of younger age. • Non-obese Covid-19 pneumonia survivors are older than obese survivors. • Age and cardiovascular disease in Covid-19 patients are not related to early death. Aims The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. Methods In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed critically ill patients from 8 hospitals throughout Greece, were analysed. All reported information stand through April 13th 2020. Results The median age of the patients was 65.5 (IQR 56-73), majority were male (80%) and obesity was present in 34.4% of patients most prevalent to younger than 55 years. Hypertension was the prevailing comorbidity (50%), followed by cardiovascular diseases (21.1%) and type-2 diabetes (18.9%). At admission, common symptoms duration had a median of 8 (IQR 5-11) days. A 13.3% of the patients were discharged, 53.4% were still in the ICUs and 28.9% deceased who were hospitalised for fewer days than the survivors [6 (IQR 3-9) vs. 9 (IQR 7-14.5) respectively]. Aging was not a risk factor but diabetes deteriorates the outcomes. Obesity poses a suggestive burden as it was more notable in deceased versus survivors. Conclusions Type 2 diabetes and obesity may have contributed to disease severity and mortality in COVID-19 critically ill patients in Greece. |
| Databáze: | OpenAIRE |
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