The Benefit of a Single Oral Dose of Ivermectin in Humans: The Adverse Effects on Cimex lectularius L. Populations and Fecundity
Autor: | Gale E. Ridge, Elizabeth R. Lesser, Xiaolin Li, Danie Schlatzer, Johnathan M. Sheele |
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Rok vydání: | 2019 |
Předmět: |
cimex lectularius
media_common.quotation_subject fecundity Population Infectious Disease 030204 cardiovascular system & hematology bedbug ivermectin reproduction 03 medical and health sciences 0302 clinical medicine Bed bug Animal science Ivermectin Cimicidae parasitic diseases Medicine education Whole blood media_common education.field_of_study biology treatment business.industry General Engineering drug cimicidae Fecundity biology.organism_classification bed bug Public Health Reproduction Cimex lectularius business Environmental Health 030217 neurology & neurosurgery infestation medicine.drug |
Zdroj: | Cureus |
ISSN: | 2168-8184 |
Popis: | Objective To measure the population size and fecundity of the common bed bug Cimex lectularius L. (C. lectularius) after feeding it with the blood obtained from human subjects who have consumed a single dose of ivermectin. Methods Serial blood samples were obtained from two human subjects at hour 0 (control) and 4-96 hours after they received a single 0.2 mg/kg dose of ivermectin. The blood samples were then fed to 2,273 bed bugs. Bed bug incapacitation rates, fecundity, and population sizes were recorded over a 54-day period. Whole blood ivermectin levels were measured in the human subjects and the insects. Results The fold change in the size of the control group population over the course of the experiment was found to be 2.16. This was significantly greater (p |
Databáze: | OpenAIRE |
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