Treatment outcome of the implementation of HIV test and treat policy at The AIDs Support Organization (TASO) Tororo clinic, Eastern Uganda: A retrospective cohort study

Autor: Kenneth Mugisha, Ronald Opito, Francis Okello, Joseph L. Mpagi, Agnes Napyo, Denis Bwayo
Rok vydání: 2020
Předmět:
Male
RNA viruses
Opportunistic infection
Epidemiology
Treatment outcome
HIV Infections
Pathology and Laboratory Medicine
Adolescents
Geographical Locations
Families
0302 clinical medicine
Medical Conditions
Immunodeficiency Viruses
Medicine and Health Sciences
Mass Screening
Uganda
030212 general & internal medicine
Child
Children
Virus Testing
0303 health sciences
education.field_of_study
Multidisciplinary
HIV diagnosis and management
Viral Load
Treatment Outcome
Infectious Diseases
Medical Microbiology
HIV epidemiology
Viral Pathogens
Viruses
Medicine
Female
Pathogens
Viral load
Research Article
Adult
medicine.medical_specialty
Adolescent
Anti-HIV Agents
Science
Population
MEDLINE
Opportunistic Infections
Vial
Microbiology
03 medical and health sciences
Young Adult
Acquired immunodeficiency syndrome (AIDS)
Diagnostic Medicine
Internal medicine
Virology
Retroviruses
medicine
Humans
education
Microbial Pathogens
Retrospective Studies
Acquired Immunodeficiency Syndrome
030306 microbiology
business.industry
Lentivirus
Organisms
Biology and Life Sciences
HIV
Retrospective cohort study
medicine.disease
Age Groups
People and Places
Africa
Population Groupings
business
Viral Transmission and Infection
Zdroj: PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0239087 (2020)
ISSN: 1932-6203
Popis: BackgroundUganda has been making progress towards universal HIV test and treat since 2013 and the 2016 test and treat policy was expanded from the 2013 guidelines. The expanded policy was rolled out in 2017 across the country. The treatment outcomes of this new policy have not yet been assessed at program level. The objective of this study was to determine the treatment outcome of the HIV test and treat policy in TASO Tororo Clinic, Eastern Uganda.MethodologyThis was a retrospective cohort study using secondary data. The study involved 580 clients who were newly diagnosed HIV positive in TASO Tororo clinic between June 2017 and May 2018, who were then followed up for ART initiation, retention in care, viral load monitoring and viral load suppression. The data was analyzed using Stat 14.0 version statistical software application.ResultsOf the 580 clients, 93.1%(540) were adults aged ≥20 years. The uptake of test and treat was at 92.4%(536) and 12 months retention was at 78.7% (422). The factors associated with retention in care were a) being counselled before ART initiation, AOR 2.41 (95%CI, 1.56-3.71), b) having a treatment supporter, AOR 1.57 (95%CI, 1.02-2.43) and having an opportunistic infection, AOR 2.99 (95%CI:1.21-7.41). The viral load coverage was 52.4% (221) and viral load suppression rate was 89.1% (197) of clients monitored. Age ConclusionThis study found high uptake of ART under test and treat policy, with very low viral load coverage, and a high viral load suppression rate among those monitored. The study therefore highlights a need to differentiate viral load testing based on the population needs and ensure each client testing positive receives pre-ART initiation counselling so as to improve retention in care.
Databáze: OpenAIRE
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