Development and validation of a modified performance-oriented mobility assessment tool for assessing mobility in children with hypophosphatasia

Autor:	Donna Griffin, Katherine L. Madson, Tracy Przybylski, Marc Vallee, Erica Morrison, Dawn Phillips, Amy Reeves, Kenji P Fujita
Rok vydání:	2018
Předmět:	medicine.medical_specialty Adolescent pediatrics Intraclass correlation Concurrent validity Hypophosphatasia Physical Therapy Sports Therapy and Rehabilitation patient outcome assessment 03 medical and health sciences mobility limitation 0302 clinical medicine Physical medicine and rehabilitation Rating scale Activities of Daily Living Medicine Humans 030212 general & internal medicine Child Gait validation studies 030203 arthritis & rheumatology Data collection business.industry Rehabilitation Reproducibility of Results early ambulation Gait analysis Child Preschool Pediatrics Perinatology and Child Health Observational study business Natural history study Psychomotor Performance Research Article
Zdroj:	Journal of Pediatric Rehabilitation Medicine
ISSN:	1875-8894
Popis:	PURPOSE: To modify the Performance-Oriented Mobility Assessment-Gait (POMA-G) subtest and validate this modified POMA-G (mPOMA-G) in children with hypophosphatasia (HPP), a rare metabolic disorder that can manifest with musculoskeletal symptoms that impair mobility and ambulation. METHODS: Based on feedback from an expert panel, the POMA-G was modified by removing gait initiation/path assessments and expanding the rating scale for step length/continuity to capture aspects of observational gait analysis relevant to children with HPP. Three trained physical therapists used the mPOMA-G for video-based assessments of gait in 14 children with childhood HPP who participated in a clinical study of asfotase alfa or in a natural history study. Intraclass correlation coefficients (ICCs) were calculated to determine interrater and intrarater agreement. Concurrent validity was evaluated by correlations with other validated assessment tools. RESULTS: Across 192 observations from available videos, interrater and intrarater agreement of mPOMA-G scores was significant (ICCs: 0.76 for both; P< 0.001). mPOMA-G scores had strong concurrent validity with the Childhood Health Assessment Questionnaire, Pediatric Outcomes Data Collection Instrument Transfer and Mobility Scale, Sports and Physical Function subscale, and 6-Minute Walk Test (all P⩽ 0.0002). CONCLUSION: The mPOMA-G is a reliable and valid measure for detecting clinically significant impairments in children with HPP.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c556353de1936b639c0b48166a324b7 https://pubmed.ncbi.nlm.nih.gov/30223404 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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