Frequency of peripheral blood eosinophilia and obstructive airway disease in sarcoidosis
| Autor: | İnsu Yılmaz, Fatma Sema Oymak, Nuri Tutar, Inci Gulmez, Burcu Baran Ketencioglu, Belal Rabah |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Allergy Adolescent Sarcoidosis Eczema Gastroenterology Pulmonary Disease Chronic Obstructive Internal medicine Eosinophilia medicine Humans Respiratory function Stage (cooking) Nose Aged Asthma Aged 80 and over business.industry General Medicine Middle Aged Airway obstruction medicine.disease Respiratory Function Tests respiratory tract diseases Airway Obstruction medicine.anatomical_structure Female medicine.symptom business |
| Zdroj: | TURKISH JOURNAL OF MEDICAL SCIENCES. 51:3001-3007 |
| ISSN: | 1303-6165 |
| DOI: | 10.3906/sag-2007-87 |
| Popis: | Background/aim: There is limited information about peripheral blood eosinophilia (PBE) and airway obstruction in sarcoidosis. Since pulmonary sarcoidosis affects the airways, it is often confused with asthma. The aims of the study are to investigate airway obstruction and PBE in sarcoidosis patients and to examine the similarity of clinical presentation with asthma. Materials and methods: The patients matching the ATS/ERS/WASOG diagnosis criteria and were between 18 and 80 years of age were included consecutively between 2018 and 2020. Other diseases causing granulomas were excluded. Results: A total of 84 patients were included of which 26 (31%) had a PBE level of >= 300 mu L with no significant difference seen between sarcoidosis stage and PBE (p > 0.05). A significant (p < 0.05) decrease was only seen in FEV1 as the stage of sarcoidosis progressed. Respectively 31 (36.9%), 12 (14.3%) and 4 (4.8%) patients had an obstructive, restrictive and mixed respiratory function disorder. Twenty-four (28.6%) subjects with sarcoidosis had history of asthma. Spring fever, eczema, and skin/nose allergy were noticed in 17 (20.2%) of the patients. Conclusion: Mild PBE may be seen in sarcoidosis. Patients applying with PBE, airway obstruction, bronchial hyperreactivity along with spring fever, eczema, skin/nose allergy, wheezing, chest tightness, shortness of breath and cough may be also evaluated in terms of sarcoidosis. |
| Databáze: | OpenAIRE |
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