Verbal autopsy: reliability and validity estimates for causes of death in the Golestan Cohort Study in Iran
| Autor: | Paul Brennan, Mehdi Nouraie, Paolo Boffetta, Akram Pourshams, Farhad Islami, Ramin Shakeri, Christian C. Abnet, Mohammad Bagheri, Hooman Khademi, Sanford M. Dawsey, Afshin Hooshyar, Behrooz Abaie, Arash Etemadi, Paul D.P. Pharoah, Farin Kamangar, Reza Malekzadeh |
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| Přispěvatelé: | Khademi, H., Etemadi, A., Kamangar, F., Nouraie, M., Shakeri, R., Abaie, B., Pourshams, A., Bagheri, M., Hooshyar, A., Islami, F., Abnet, C.C., Pharoah, P., Brennan, P., Boffetta, P., Dawsey, S.M., Malekzadeh, R. |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
Gerontology validity medicine.medical_specialty Validation study Public Health and Epidemiology lcsh:Medicine Autopsy causes of death Iran Cohort Studies Cause of Death Surveys and Questionnaires parasitic diseases Epidemiology medicine Humans Verbal autopsy Evidence-Based Healthcare/Methods for Diagnostic and Therapeutic Studies lcsh:Science Reliability (statistics) Aged Cause of death Multidisciplinary business.industry Medical record lcsh:R golestan cohort study Reproducibility of Results Middle Aged Reliability Female lcsh:Q Public Health and Epidemiology/Epidemiology business geographic locations Research Article Cohort study Demography |
| Zdroj: | PLoS ONE, Vol 5, Iss 6, p e11183 (2010) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Background: Verbal autopsy (VA) is one method to obtain valid estimates of causes of death in the absence of valid medicalrecords. We tested the reliability and validity of a VA questionnaire developed for a cohort study in Golestan Province in northeastern Iran. Method: A modified version of the WHO adult verbal autopsy was used to assess the cause of death in the first 219 Golestan Cohort Study (GCS) subjects who died. The GCS cause of death was determined by two internists who independently reviewed all available medical records. Two other internists ("reviewers") independently reviewed only the VA answers and classified the cause of death into one of nine general categories; they repeated this evaluation one month later. The reliability of the VA was measured by calculating intra-reviewer and inter-reviewer kappa statistics. The validity of the VA was measured using the GCS cause of death as the gold standard. Results: VA showed both good validity (sensitivity, specificity, PPV, and NPV all above 0.81) and reliability (kappa.0.75) in determining the general cause of death independent of sex and place of residence. The overall multi-rater agreement across four reviews was 0.84 (95%CI: 0.78-0.89). The results for identifying specific cancer deaths were also promising, especially for upper GI cancers (kappa = 0.95). The multi-rater agreement in cancer subgroup was 0.93 (95%CI: 0.85-0.99). Conclusions: VA seems to have good reliability and validity for determining the cause of death in a large-scale adult follow up study in a predominantly rural area of a middle-income country. |
| Databáze: | OpenAIRE |
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