Fat-soluble vitamin concentration in chronic alcohol-induced pancreatitis
| Autor: | D. Labadarios, I. N. Marks, Francesco Marotta, A. Girdwood, L. Frazer |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Vitamin medicine.medical_specialty Pancreatic disease Adolescent Physiology medicine.medical_treatment chemistry.chemical_compound Crohn Disease Internal medicine Blood plasma medicine Humans Vitamin E Vitamin A Aged Gastroenterology Retinol Vitamins Middle Aged medicine.disease Lipids digestive system diseases Steatorrhea Retinol-Binding Proteins Alcoholism Celiac Disease Fat-Soluble Vitamin Endocrinology Pancreatitis Solubility chemistry Chronic Disease Female medicine.symptom Retinol-Binding Proteins Plasma |
| Zdroj: | Digestive Diseases and Sciences. 39:993-998 |
| ISSN: | 1573-2568 0163-2116 |
| DOI: | 10.1007/bf02087550 |
| Popis: | In order to study the fat-soluble vitamin concentration of patients with chronic alcohol-induced pancreatitis (CAIP) we measured vitamins A and E, total lipids, and retinol-binding protein (RBP) in the plasma of 44 patients with CAIP and 83 controls (44 healthy controls; 39 Crohn's disease patients). Mean plasma vitamin E and vitamin E/total lipid ratio were significantly lower in CAIP when compared with either control or Crohn's disease groups. A low vitamin E/total lipid ratio was found in 75% of CAIP patients (91% with steatorrhea) and a ratio less than 1.0 was virtually 100% predictive of steatorrhea. The mean plasma vitamin A level for the CAIP group was significantly lower (overall 16%, 38% with steatorrhea) than in controls. Patients with CAIP show subnormal plasma levels vitamin E more often as compared to vitamin A. Further, the plasma vitamin E/total lipids ratio may be a sensitive and practical means in the detection and follow-up of steatorrhea in these patients. |
| Databáze: | OpenAIRE |
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