Long- term remission status in pediatric obsessive-compulsive disorder: Evaluating the predictive value of symptom severity after treatment
| Autor: | Sanne Jensen, Erik L. Mortensen, Gudmundur Skarphedinsson, David RMA Højgaard, Katja A. Hybel, Judith B. Nissen, null Tord Ivarsson, Bernhard Weidle, Nor C. Torp, Per H. Thomsen |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Obsessive-Compulsive Disorder
Children and adolescents Cognitive Behavioral Therapy OCD Remission NONRESPONDERS Clinical assessment Clinical global impression scale CHILDREN Children?s Yale-brown obsessive-compulsive Stepped-care treatment COGNITIVE-BEHAVIOR THERAPY Long-term study Psychiatry and Mental health Stepped -care treatment DEFINING TREATMENT RESPONSE SIGNAL-DETECTION ANALYSIS RELIABILITY ADOLESCENTS Humans Children's Yale-brown obsessive-compulsive scale Child FOLLOW-UP PSYCHOMETRIC EVALUATION Biological Psychiatry |
| Zdroj: | Jensen, S, Mortensen, E L, Skarphedinsson, G, Hojgaard, D R M A, Hybel, K A, Nissen, J B, Ivarsson, T, Weidle, B, Torp, N C & Thomsen, P H 2022, ' Long-term remission status in pediatric obsessive-compulsive disorder : Evaluating the predictive value of symptom severity after treatment ', Psychiatry Research, vol. 317, 114906 . https://doi.org/10.1016/j.psychres.2022.114906 Psychiatry Research Jensen, S, Mortensen, E L, Skarphedinsson, G, Højgaard, D RMA, Hybel, K A, Nissen, J B, Tord Ivarsson, I, Weidle, B, Torp, N C & Thomsen, P H 2022, ' Long-term remission status in pediatric obsessive-compulsive disorder : Evaluating the predictive value of symptom severity after treatment ', Psychiatry Research, vol. 317, 114906 . https://doi.org/10.1016/j.psychres.2022.114906 |
| DOI: | 10.1016/j.psychres.2022.114906 |
| Popis: | It is unknown if long-term remission for pediatric obsessive-compulsive disorder (OCD) patients is associated with post-treatment OCD symptom severity. The aim of the present study was to evaluate if post-treatment symptom severity cut-offs can discriminate remitters from non-remitters in pediatric OCD patients during three years of follow-up. All participants (N = 269) from the Nordic Long-term OCD Treatment Study (Nor-dLOTS) undergoing stepped-care treatment were included. Patients were rated with the Clinical Global Impression - Severity Scale (CGI-S) one (n = 186), two (n = 167), and three years (n = 166) after first-line cognitive-behavioral therapy. Post-treatment symptom severity scores as well as percentage reductions during treatment evaluated with the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) were analyzed using receiver operating characteristics according to the CGI-S remission scores (< 2) at follow-up. Post-treatment CY-BOCS severity scores acceptably discriminated remitters from non-remitters at one-year follow-up, but poorly for the two-and three-year follow-up. Severity percentage reduction during treatment did not discriminate remis-sion status acceptably at any follow-up point. Post-treatment OCD symptom severity status seems to have little discriminative value for long-term remission status in pediatric patients. Further research is warranted to detect post-treatment factors of prognostic value. |
| Databáze: | OpenAIRE |
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