The Laboratory Features of Congenital Hypothyroidism and Approach to Therapy
| Autor: | Alyson Weiner, Patricia M. Vuguin, Sharon E. Oberfield |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
endocrine system
Pediatrics medicine.medical_specialty endocrine system diseases Thyroid Function Tests Thyroid function tests Article Infant Newborn Diseases 03 medical and health sciences Neonatal Screening 0302 clinical medicine 030225 pediatrics Intellectual disability Congenital Hypothyroidism medicine Central hypothyroidism Humans 030212 general & internal medicine Newborn screening medicine.diagnostic_test business.industry Thyroid Infant Newborn medicine.disease Congenital hypothyroidism medicine.anatomical_structure Pediatrics Perinatology and Child Health Etiology business Hormone |
| Zdroj: | Neoreviews |
| ISSN: | 1526-9906 |
| DOI: | 10.1542/neo.21-1-e37 |
| Popis: | Congenital hypothyroidism (CH) is one of the most common preventable causes of intellectual disability. Thyroid hormone is required for normal brain development, but neonates with CH typically appear healthy at birth, which leads to delays in diagnosis and treatment. In developed countries, newborn screening programs have led to earlier diagnosis and treatment of CH, resulting in improved neurodevelopmental outcomes. Neonates with an abnormal newborn screen require prompt confirmatory serum thyroid function tests and treatment with thyroid hormone. Further evaluation for the etiology of CH should not delay treatment decisions. |
| Databáze: | OpenAIRE |
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