Self-assessment of pubertal development in a puberty cohort

Autor: Lea Lykke Braskhøj Lauridsen, Andreas Ernst, Lars Henning Olsen, Camilla Kjersgaard, Niels Clausen, Erik T. Parner, Jørn Olsen, Cecilia Høst Ramlau-Hansen, Nis Brix
Rok vydání: 2018
Předmět:
Zdroj: Ernst, A, Lauridsen, L L B, Brix, N, Kjersgaard, C, Olsen, J, Parner, E T, Clausen, N, Olsen, L H & Ramlau-Hansen, C H 2018, ' Self-assessment of pubertal development in a puberty cohort ', Journal of Pediatric Endocrinology and Metabolism, vol. 31, no. 7, pp. 763-772 . https://doi.org/10.1515/jpem-2018-0178
ISSN: 2191-0251
0334-018X
DOI: 10.1515/jpem-2018-0178
Popis: Background We evaluated the inter-rater agreement between self-assessed Tanner staging and clinical examination and the intra-individual agreement of self-assessed information on various puberty markers in late adolescents from the longitudinal nationwide Puberty Cohort, a sub-cohort of the Danish National Birth Cohort (DNBC). Methods We invited 715 children from the ongoing Puberty Cohort between June 2016 and January 2017. In total, 366 children (51%) returned an add-on questionnaire identical to the questionnaire used to collect information on puberty markers, including Tanner staging, in the Puberty Cohort. Of these, 197 (54%) also participated in a clinical examination with Tanner staging. We used percentage agreement and weighted kappa statistics to evaluate the inter-rater and intra-individual agreement. Results Due to late entry, more than 75% of children were Tanner stage 4 or above at clinical examination. In girls, the inter-rater agreement for pubic hair and breast staging was 54% and 52%, respectively, yielding weighted kappas of fair strength. In boys, pubic hair and genital staging agreed in 55% and 33%, respectively, corresponding to weighted kappas of fair to moderate strength. Boys tended to underestimate genitalia staging consistently. The intra-individual agreement on Tanner staging was 75–77% in girls and 69% in boys, whereas the intra-individual agreement on axillary hair and acne was above 92%. Conclusions Self-assessment of late stages of pubertal development may be misclassified, leading to random errors in studies of puberty timing. However, self-assessment continues to serve as an important time- and cost-saving tool in large prospective puberty cohorts.
Databáze: OpenAIRE