The use of autologous platelet-leukocyte gels to enhance the healing process in surgery, a review
| Autor: | A. van Zundert, J.J. Jakimowicz, E.P. Overdevest, C.J.M. Oosterbos, Johannes T. A. Knape, Jacques P.A.M. Schönberger, P.A. Everts |
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| Přispěvatelé: | University of Groningen |
| Rok vydání: | 2006 |
| Předmět: |
Blood Platelets
medicine.medical_specialty Soft Tissue Injuries Bone healing Transplantation Autologous MESENCHYMAL STEM-CELLS BONE REGENERATION DELIVERY Drug Delivery Systems growth factors Medicine and Health Sciences medicine Leukocytes Animals Humans Surgical Wound Infection Bone regeneration Fibrin glue platelet gel GROWTH-FACTORS MICROBICIDAL PROTEINS REPAIR Fracture Healing Platelet-Derived Growth Factor Biological Products Wound Healing RICH PLASMA Tissue Engineering business.industry Hemostasis Endoscopic PROLIFERATION Soft tissue FIBRIN GLUE Surgery Hernia Abdominal Transplantation CONCENTRATE Plastic surgery Treatment Outcome Hemostasis Surgical Procedures Operative Wound healing business Gels |
| Zdroj: | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES Surgical endoscopy and other interventional techniques, 21(11), 2063-2068. SPRINGER |
| ISSN: | 1432-2218 0930-2794 |
| Popis: | Background: The therapeutic use of autologously prepared, platelet-leukocyte-enriched gel (PLG) is a relatively new technology for the stimulation and acceleration of soft tissue and bone healing. The effectiveness of this procedure lies in the delivery of a wide range of platelet growth factors mimicking the physiologic wound healing and reparative tissue processes. Despite an increase in PLG applications, the structures and kinetics of this autogenously derived biologic material have not been observed.Methods: A review of the most recent literature was performed to evaluate the use of PLG in various surgical disciplines.Results: The review showed that the application of PLG has been extended to various surgical disciplines including orthopedics, cardiac surgery, plastic and maxillofacial surgery, and recently also endoscopic surgery.Conclusion: This review demonstrates the usefulness of PLG in a wide range of clinical applications for improvement of healing after surgical procedures. |
| Databáze: | OpenAIRE |
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