Content of testosterone and activity of 5α-steroid-NAD(P)Δ4-oxidoreductase in normal bone tissue and malignant bone tumors
| Autor: | S. A. Chukaev, P. V. Sergeev, N. E. Kushlinskii, E. V. Gorbatenko |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty medicine.medical_treatment General Medicine Biology Bone tissue General Biochemistry Genetics and Molecular Biology In vitro Steroid medicine.anatomical_structure Primary bone Endocrinology Enzyme chemistry Oxidoreductase Internal medicine medicine NAD+ kinase Testosterone |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf02446994 |
| Popis: | Optimal conditions for measuring 5α-steroid-NAD(P)Δ4-oxidoreductase in primary bone tumors and in normal bone tissues are experimentally chosenin vitro. It is shown that the bone belongs to tissues with low activity of this enzyme. A considerable activation of 5α-steroid-NAD(P)Δ4-oxidoreductase is found in primary bone tumors, the content of testosterone being unchanged. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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