Early incidence of occupational asthma is not accelerated by atopy in the bakery/pastry and hairdressing sectors

Autor: Dovi-Stéphanie Acouetey, B. Hannhart, A. Barbaud, Christophe Paris, Mathias Poussel, Thomas Remen, Bruno Chenuel, Denis Zmirou-Navier
Přispěvatelé: Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Développement, Adaptation et Handicap. Régulations cardio-respiratoires et de la motricité (DevAH), Université de Lorraine (UL), Faculté de Médecine [Nancy]
Rok vydání: 2013
Předmět:
Zdroj: International Journal of Tuberculosis and Lung Disease
International Journal of Tuberculosis and Lung Disease, International Union Against Tuberculosis and Lung Disease, 2013, 17 (7), pp.973-81. ⟨10.5588/ijtld.12.0864⟩
ISSN: 1027-3719
1815-7920
DOI: 10.5588/ijtld.12.0864
Popis: International audience; SETTING: Occupational asthma (OA) is most likely to develop in the very early years of exposure. OBJECTIVE: To describe the early incidence of OA among bakers/pastry-makers (BP) and hairdressers and to explore the role of atopy. DESIGN: Following a retrospective follow-up design, subjects were invited to undergo telephone interviews. Those who declared work-related respiratory or rhinitis symptoms and a sample group of others were offered a medical visit for OA investigations. Data from interviews and from medical visits were used to estimate the incidence of OA according to increasing durations of exposure. RESULTS: A total of 866 subjects were interviewed (mean age 25.3 years, 43.8% females), of whom 282 underwent a medical visit. Total estimated incidence rates of 'confirmed or probable' OA during the first 12 years of exposure were high in BP (2.63 per 100 person-years [py]) and in hairdressers (0.58/100 py), particularly in the first 4 years. Atopy is a strong risk factor for incidence among BP but, irrespective of the occupational sector, it does not influence the timing of OA symptoms. CONCLUSION: OA symptoms occur soon after the start of exposure. Our results suggest that atopy does not precipitate the occurrence of symptoms in two different allergen exposure settings.
Databáze: OpenAIRE