A novel oxidative side-chain transformation of α-amino acids and peptides by methyltrioxorhenium/H2O2 system

Autor:	Marcello Crucianelli, Raffaele Saladino, Francesco De Angelis, Veronica Neri, Francesco Lazzaro
Rok vydání:	2004
Předmět:	chemistry.chemical_classification Chemistry Stereochemistry Organic Chemistry Regioselectivity Homogeneous catalysis Oxidative phosphorylation Biochemistry Amino acid chemistry.chemical_compound Transformation (genetics) Drug Discovery Side chain Amino acid residue Hydrogen peroxide
Zdroj:	Tetrahedron Letters. 45:9237-9240
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.10.074
Popis:	N-Boc derivatives of Met, Cys, and Trp, the properties of which resemble those of the respective amino acid residues present in proteins, are efficiently oxidized by methyltrioxorhenium and H2O2. A high regioselectivity for the oxidation of these residues when embedded into peptides was also found.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2e31073109b34613056f00d1d27248 https://doi.org/10.1016/j.tetlet.2004.10.074 Zobrazit plný text záznamu Full Text from ScienceDirect