The combination of traditional and auricular acupuncture to prevent xerostomia and anxiety in irradiated patients with HNSCC: a preventive, parallel, single-blind, 2-arm controlled study

Autor: Agna Soares da Silva Menezes, Raquel Gusmão Soares, Sérgio Henrique Sousa Santos, Gabriela Luize Guimarães Sanches, Alfredo Maurício Batista de Paula, Adriana Aparecida Almeida de Aguiar Ribeiro, Lucyana Conceição Farias, André Luiz Sena Guimarães, Jairo Evangelista Nascimento, Arlen de Paulo Santiago Filho, Larissa Lopes Fonseca, Cristina Paixão Durães, Emisael Stênio Batista Gomes
Rok vydání: 2021
Předmět:
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 131:675-683
ISSN: 2212-4403
DOI: 10.1016/j.oooo.2021.02.016
Popis: Objective The purpose of the present study was to investigate the effect of acupuncture on xerostomia in irradiated patients with head and neck squamous cell carcinoma (HNSCC). Study Design A preventive, 2-arm, parallel, single-blind trial was performed. Patients with HNSCC (N = 296) were checked for eligibility, and 107 patients were enrolled in the study. The study comprised 1 group that did not receive the intervention (n = 55) and the interventional group that received traditional and auricular acupuncture (n = 52). The primary outcome was the reduction of the patients’ xerostomia after treatment. In addition, the secondary outcome was the reduction of anxiety. Results The current acupuncture protocol reduced the xerostomia score and increased saliva volume and density without changing salivary pH. Additionally, acupuncture decreased the Beck Anxiety Inventory (BAI) score after radiation therapy. Conclusion Combining traditional and auricular acupuncture reduced xerostomia and increased saliva volume without changing the saliva's pH in irradiated patients with HNSCC. Additionally, the combination of traditional and auricular acupuncture reduced BAI scores.
Databáze: OpenAIRE