Effects of omega-3 fatty acids on working memory in rats with increased sugar intake
| Autor: | Ewelina Stollberg, Klaus W. Lange, Yukiko Nakamura, Joachim Hauser, Ivo Kaunzinger, Stefanie Ruhland |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Medicine (miscellaneous) Sugar consumption 03 medical and health sciences 0404 agricultural biotechnology Cognition Sugar intake Internal medicine Fourth generation medicine Omega-3 fatty acids TX341-641 Sugar 030109 nutrition & dietetics Nutrition and Dietetics Radial arm maze business.industry Working memory Nutrition. Foods and food supply 04 agricultural and veterinary sciences 040401 food science Endocrinology Rat High sugar business Food Science |
| Zdroj: | Journal of Functional Foods, Vol 69, Iss, Pp 103951-(2020) |
| ISSN: | 1756-4646 |
| Popis: | The “Western” diet, with its high sugar content and low levels of omega-3 fatty acids (n-3), has been linked to various cognitive deficits and mental disorders in animal models and humans. We have examined whether a dietary deficiency in n-3 in combination with increased sugar consumption affects working memory in rats. Wistar rats were bred and fed a high-sugar diet over several generations. The animals were randomly assigned to two groups: a group receiving physiologically adequate amounts of n-3 and a group fed an n-3-deficient diet. Thirty-one male, fourth generation rats were tested in a radial arm maze in order to assess working memory performance. Compared to rats receiving a diet with sufficient n-3, the n-3-deprived animals erred more frequently on working memory tasks, indicating that n-3 reduction in rats on a sugar-rich diet may have negative effects on working memory additional to those associated with high sugar consumption. |
| Databáze: | OpenAIRE |
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