Recognizing Hyperviscosity Syndrome in Patients With Waldenstrom Macroglobulinemia
| Autor: | Michael Wang, Ellen Mullen |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Blood viscosity Vision Disorders Antineoplastic Agents Hemorrhage Nurse's Role Gastroenterology Dyscrasia Patient Education as Topic Internal medicine Hyperviscosity syndrome medicine Humans Confusion Referral and Consultation Fatigue Nursing Assessment General Environmental Science Aged 80 and over Information Services Salvage Therapy Internet Chemotherapy medicine.diagnostic_test business.industry Oncology Nursing Waldenstrom macroglobulinemia Bone Marrow Examination Syndrome Blood Coagulation Disorders Blood Viscosity medicine.disease Bone marrow examination Practice Guidelines as Topic General Earth and Planetary Sciences Female Rituximab Plasmapheresis Waldenstrom Macroglobulinemia business Stem Cell Transplantation medicine.drug |
| Zdroj: | Clinical Journal of Oncology Nursing. 11:87-95 |
| ISSN: | 1538-067X 1092-1095 |
| DOI: | 10.1188/07.cjon.87-95 |
| Popis: | Hyperviscosity syndrome can develop in patients with plasma cell dyscrasias, particularly Waldenstrom macroglobulinemia (WM). Occurring in 10%-30% of patients with hyperviscosity syndrome, WM is an uncommon B-cell proliferative disorder characterized by bone marrow infiltration and production of monoclonal immunoglobulin M. The elevated blood viscosity in WM is the result of increased circulating serum immunoglobulin M. Because hyperviscosity syndrome can be lethal, it must be recognized and managed early. Hyperviscosity syndrome has a triad presentation: vision changes, neurologic abnormalities, and bleeding. Treatment includes hydration with diuresis, plasmapheresis, and control of the underlying disease. The current treatment for WM is chemotherapy (i.e., alkylating agents and nucleoside analogs) and the monoclonal antibody rituximab. Although hyperviscosity syndrome is not one of the most common conditions, when it does occur, oncology nurses play a critical role in patients' assessment and care. |
| Databáze: | OpenAIRE |
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