Could both intrinsic and extrinsic iodine be successfully suppressed on virtual non-contrast CT images for detecting thyroid calcification?

Autor: Young Hen Lee, Hyung Suk Seo, Arim Park
Rok vydání: 2021
Předmět:
Zdroj: Japanese Journal of Radiology. 39:580-588
ISSN: 1867-108X
1867-1071
DOI: 10.1007/s11604-021-01095-8
Popis: Although virtual non-contrast (VNC) successfully removes iodinated contrast, uncertainty exists regarding the feasibility of VNC to suppress iodine for detecting thyroid calcification. Therefore, we evaluated whether both intrinsic and extrinsic iodine attenuation were suppressed on VNC images. We enrolled 128 patients (male: female 17:111; age 48.0 ± 10.4 years) who underwent dual-layer dual-energy CT (DL-DECT) examination before their thyroid cancer surgeries. Two additional sets of VNC (VNCu, VNCc) images were retrospectively generated from their true unenhanced (TUE) and true contrast-enhanced (TCE) series. We compared CT attenuation values measured on the VNCu and VNCc images by drawing identical regions of interest encompassing thyroid parenchyma, then subjectively determined the concordance of calcification. Although CT attenuation discrepancies between the VNCu and VNCc were significant (2.0 ± 5.7HU, p
Databáze: OpenAIRE