Orally active non-peptide fibrinogen receptor (GpIIb/IIIa) antagonists: identification of 4-[4-[4-(aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid as a long-acting, broad-spectrum antithrombotic agent
| Autor: | C D, Eldred, B, Evans, S, Hindley, B D, Judkins, H A, Kelly, J, Kitchin, P, Lumley, B, Porter, B C, Ross, K J, Smith |
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| Rok vydání: | 1994 |
| Předmět: |
Blood Platelets
Fibrinogen receptor Stereochemistry Administration Oral Platelet Membrane Glycoproteins Fibrinogen Piperazines Amidine chemistry.chemical_compound Structure-Activity Relationship Fibrinolytic Agents Piperidines Oral administration Drug Discovery medicine Animals Humans Platelet Antagonist Callithrix Long acting Orally active chemistry Molecular Medicine Platelet Aggregation Inhibitors medicine.drug |
| Zdroj: | Journal of medicinal chemistry. 37(23) |
| ISSN: | 0022-2623 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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