Sulphitolysis in keratinolysis. Biochemical proof
| Autor: | Suzanne Andrieu, G. Biserte, P. Ruffin, J. Biguet |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
chemistry.chemical_classification
Enzymic hydrolysis Chemistry Ion chromatography Microsporum gypseum General Medicine In Vitro Techniques medicine.disease_cause Keratinomyces ajelloi Culture Media Hydrolysis Infectious Diseases Trichophyton Biochemistry Keratin Dermatophyte medicine Humans Keratins Cysteine Hair |
| Zdroj: | Medical Mycology. 14:181-184 |
| ISSN: | 1460-2709 1369-3786 |
| DOI: | 10.1080/00362177685190251 |
| Popis: | The presence of S-sulphocysteine in filtrates of the dermatophyte Keratinomyces ajelloi growing on human hair in a culture medium buffered by pH 7·4 by phosphates was demonstrated by means of ion exchange chromatography techniques. S-sulphocysteine being destroyed during acidic hydrolysis was identified after enzymic hydrolysis of dialyzed and lyophilized filtrates. This result indicates that sulphitolysis occurs during keratinolysis performed by K. ajelloi. As thiosulphuric esters were shown present in hair perforations made by Microsporum gypseum, we think sulphitolysis is a common mechanism developed by dermatophytes to attack keratin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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