Supplementary Figure 3: Dinaciclib reduces the mRNA transcripts of Rad51, its paralogs and Brca1 in vivo from A Cyclin-Dependent Kinase Inhibitor, Dinaciclib, Impairs Homologous Recombination and Sensitizes Multiple Myeloma Cells to PARP Inhibition
| Autor: | Robert J. Shmookler Reis, Shmuel Yaccoby, Srinivas Ayyadevara, David A. Alagpulinsa |
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| Rok vydání: | 2023 |
| DOI: | 10.1158/1535-7163.22503487 |
| Popis: | When tumor volumes had reached the predetermined limit, as indicated in Materials and Methods, the treatments were repeated for 24 h and tumors excised and immediately preserved in RNAlater. Total RNA was extracted from the tumors and subjected to RT-qPCR as described in the Materials and Methods. Results represent the mean {plus minus} SEM of at least 3 mice from each treatment group. *, **, *** and **** indicate significance of differences from DMSO controls, at p |
| Databáze: | OpenAIRE |
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