Use of C7 Slope as a Surrogate Marker for T1 Slope: A Radiographic Study in Patients with and without Cervical Deformity
| Autor: | Manish K. Kasliwal, Arunit J. S. Chugh, Christina Gerges, Kerrin Sunshine, Mohit Patel, Betsy Wilson |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Radiography Kyphosis Thoracic Vertebrae 03 medical and health sciences 0302 clinical medicine Cervical deformity Deformity medicine Humans Aged Retrospective Studies Orthodontics Cobb angle business.industry Surrogate endpoint Middle Aged medicine.disease Sagittal plane medicine.anatomical_structure Cross-Sectional Studies 030220 oncology & carcinogenesis Coronal plane Cervical Vertebrae Lordosis Surgery Female Neurology (clinical) medicine.symptom business Tomography X-Ray Computed 030217 neurology & neurosurgery |
| Zdroj: | World neurosurgery. 143 |
| ISSN: | 1878-8769 |
| Popis: | T1 slope has emerged as an important radiographic parameter in the evaluation and surgical management of adult cervical spinal deformity. Given the high rates of nonvisualization of T1 slope on upright cervical radiographs, however, this study examined the evaluation of C7 slope as a potential surrogate marker.This is a retrospective review in adult patients with and without cervical deformity to examine the correlation of C7 and T1 slopes on routine upright cervical radiographs. In secondary analysis, correlations of C7 and T1 slopes were made amongst various demographic variables, different surgical groups, and various measures of cervical alignment. Cervical deformity was defined as sagittal vertical axis40 mm, coronal Cobb angle10°, and sagittal Cobb10° in kyphosis.C7 slope was visualized in 93% of patients as opposed to T1 slope in 68% of patients, leading to a final study population of 129 patients. Mean values of C7 and T1 slopes were 26.5° and 28.1°, respectively. Significant correlation was found in patients with and without cervical deformity (r = 0.9, P0.01). This correlation remained significant amongst demographics, surgical groups, and measures of cervical alignment.Results demonstrated that C7 and T1 were in direct correlation in a variety of different cohorts regardless of deformity status or prior fusion. This study indicates that C7 slope may be reliably used a surrogate marker especially when visualization of T1 slope is not possible. |
| Databáze: | OpenAIRE |
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