Postoperative complications and myocardial injury in patients receiving air or oxygen. Prospective, randomised and pilot study

Autor: Arman Valadkhani, Ragnar Henningsson, Johan L. Nordström, Anna Granström, Linn Hallqvist, Carl Magnus Wahlgren, Bengt Peterzén, Julia Eriksson, Max Bell, Anil Gupta
Rok vydání: 2022
Předmět:
Zdroj: Acta Anaesthesiologica Scandinavica. 66:1185-1192
ISSN: 1399-6576
0001-5172
DOI: 10.1111/aas.14136
Popis: Supplementary oxygen is administered during anaesthesia to increase oxygen delivery and prevent hypoxia. Recent studies have questioned this routine. In this pilot study, our main aim was to investigate if 21% oxygen compared to ≥50% reduces the risk of postoperative complications and myocardial injury.In this pragmatic, multicentre, single-blind study, patients undergoing vascular surgery were randomised to receive a fraction of inspired oxygen (FThe 191 patients were randomised, and per-protocol principle was used for analyses. At 30-day follow-up, 43 out of 94 patients (46%) had a postoperative complication in group H and 36 out of 90 patients (40%) in group N, p = .46. New myocardial injury was seen in 27% versus 22% in Groups H and N respectively (p = .41). No differences in other outcomes were observed between the groups. Twelve patients (13%) in Group N had SpOIn this pilot study, postoperative complications were similar between the groups in patients randomised to F
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje